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How To Use PDT Photon Therapy Device?


Specialized healthcare equipment called photon therapy devices are used in the procedure of photodynamic therapy. A photosensitizing agent and light exposure are combined in photodynamic therapy (PDT) to activate the agent and provide a therapeutic effect. These devices generate light at particular wavelengths that trigger the photosensitizing chemical applied over the treatment area, causing abnormal cells to be selectively destroyed.


What is Photodynamic Therapy (PDT)?

Photodynamic therapy (PDT) creates a photochemical reaction using photosensitizing chemicals, oxygen, and light that targets cancer cells selectively. The medications known as photosensitizing agents are injected, ingested, or applied topically. When light, oxygen, and photosensitizing agents interact, they produce various free radicals, such as single-molecule oxygen, hydroxyl radicals, and superoxides. Interactions between these reactive species and targeted cellular structures cause cell death, thus removing the targeted cells.
What are PDT devices? How can we use it? Where can we find it? Let’s get answers to these in detail.
Types of PDT Photon Therapy Devices

  1.  Handheld Devices
  2.  Panel Devices
  3.  Mask Devices
  4.  Intravenous Devices
AspectHandheld DevicesPanel DevicesMask DevicesIntravenous Devices
DescriptionPortable, small, user-friendly devicesLarge, flat panels for broad light coverageWearable masks designed for facial treatmentsDevices using fiber optics to deliver light internally
Light SourceLEDs or lasersLEDs or fluorescent lampsLEDsLaser or LED systems with fiber optics
Wavelength Range400-700 nm (varies by model)400-700 nm (varies by model)400-700 nm600-1200 nm
Treatment AreaSmall, localized areasLarge, extensive areasFace and neck areasInternal body regions, such as esophagus or bladder
Typical ApplicationsAcne, small actinic keratoses, superficial skin lesionsExtensive actinic keratoses, psoriasis, and large skin cancersFacial rejuvenation, acne, and hyperpigmentationInternal cancers (e.g., esophageal cancer)
CostLow to moderateHighModerateVery high
Safety FeaturesAutomatic shut-off, cooling mechanisms, eye protectionAutomatic shut-off, cooling systemsAutomatic shut-off, skin-friendly materialsAdvanced safety protocols to prevent internal damage
LimitationsLimited to small areas, lower powerRequires clinical setting and a higher costLimited to face and neck, moderate costRequires specialized equipment and professional use
MaintenanceLow; simple cleaning and occasional part replacementModerate; requires regular maintenanceLow; similar to handheld devicesHigh; requires specialized maintenance and calibration
Clinical EvidenceEffective for small skin lesions and acneProven for large-scale treatments like psoriasis and widespread actinic keratosesEffective for facial rejuvenation and acne treatmentEffective for internal cancers with targeted light delivery

 How to Use PDT Devices?

Photodynamic Therapy (PDT) devices function by using light-activated photosensitizing chemicals to treat a variety of skin problems. Efficiency and safety are ensured by using these devices carefully. The detailed instructions for using PDT equipment, which apply to both handheld and bigger clinical devices, are provided below.

 General Steps for Using PDT Devices

 1. Consultation and Diagnosis

Consult a healthcare professional to determine the condition’s diagnosis and PDT suitability before utilizing any PDT devices. This stage helps determine the ideal photosensitizing agent and light settings and guarantees that PDT is an appropriate method for action.

 2. Preparation

Clean the Treatment Area: Make sure the skin is free of oil, dust, or makeup. Better photosensitizing agent penetration is ensured by doing this.

Apply Photosensitizing Agent: Depending on the situation, the target area is treated with a photosensitizing agent (such as methyl aminolevulinate or aminolevulinic acid). Although this can be administered intravenously, orally, or topically, topical administration is more frequently used for skin disorders.

 3. Incubation Period

Let the cells absorb the photosensitizing agent. The length of the incubation period, which can range from 30 minutes to a few hours, depends on the substance being used and the condition that is being treated.

 4. Light Activation

Position the Device: Align the PDT device such that it is over or close to the treatment region. Make sure the light source is positioned correctly to illuminate the whole target area.

Adjust Settings: As advised by your healthcare physician or the device handbook, set the device’s wavelength and power settings appropriately.

Duration: For the designated amount of time—usually 10 to 30 minutes for portable devices, longer for bigger equipment—expose the treatment area to the light.

 5. Post-Treatment Care

Clean this area: To get rid of any residual photosensitizing chemicals, gently clean the region after the treatment.

Apply Soothing Agents: To reduce inflammation and encourage healing, apply a soothing or anti-inflammatory lotion.

Avoid sunlight: As the skin will be hypersensitive, avoid going out in sunlight, and if you have to go outside, apply sunscreen.


Specific Instructions for Different PDT Devices

 Handheld Devices

1. Charge the device: Ensure that the device is either plugged in or completely charged.

2. Application: After applying the photosensitizing agent to the desired area, allow it to incubate for some time.

3. Light Exposure: Switch on the portable device, select an appropriate level of light, and cover the treatment area with it while holding it close to the skin. If necessary, move the device slowly to evenly cover all areas.

4. Post-Treatment: Follow the standard post-treatment care instructions.

 Panel and Mask Devices

1. Setup: Position the panel stably above the treatment area. And make sure the mask covers the face securely and comfortably.

2. Application: After applying the photosensitizing agent, allow it some time to incubate.

3. Light Exposure: Set up the patient such that the light from the panel hits the treatment area. And adjust the mask for the recommended period of time. Make sure the patient doesn’t move throughout the exposure period.

4. Post-Treatment: Adhere to standard post-treatment care instructions.

Intravenous Devices

1. Administration: Professional setup and monitoring are required for these devices. The intravenous administration of the photosensitizing agent is done.

2. Application: Fiber optics are used to provide light internally to the target area, such as the bladder or esophagus.

3. Light Exposure: The medical professional will make sure that the right amount and duration of light exposure are employed.

4. Post-Treatment: Adhere to physician guidance for post-treatment care; this may include particular guidelines depending on the area that was treated.

Why are PDT devices a better choice? Comparison with Other Technologies.

FeaturePDT Photon Therapy DevicesLaser TherapyLED Light TherapyUV Therapy
MechanismUses light-sensitive agents activated by lightUses concentrated light beamsUses light-emitting diodesUses ultraviolet light
ApplicationsSkin conditions, cancer, inflammation.
Studies report a 70-90% reduction in acne lesions after multiple PDT sessions.Skin resurfacing, hair removalSkin rejuvenation, acne treatmentPsoriasis, eczema
Side EffectsMinimal, localizedPotential burns, rednessMinimal, mild skin irritationSkin aging, risk of cancer
CostModerate to highHighLow to moderateLow


For a range of medical conditions, PDT Photon Therapy Devices provide an adaptable, non-invasive, and efficient therapeutic option. They are an essential instrument in both home and professional healthcare settings because of their ability to target particular locations with minimal adverse effects. It is anticipated that PDT’s use and efficacy will grow as technology develops, giving patients even more advantages.


1. Does PDT work well for treating acne?

Yes. A study published in the Journal of the American Academy of Dermatology showed that PDT significantly reduced acne lesions. Patients treated with a combination of 5-aminolevulinic acid (a photosensitizer) and blue light exhibited a 70-90% reduction in acne severity after multiple sessions (Gold et al., 2004).

2. Which PDT device is best?

When choosing the best PDT equipment, factors such as the user’s needs, the treatment position, and the specific medical condition are taken into consideration.

– Because they are portable and easy to use, handheld and mask devices are suitable for use at home.

– For professional use: Panel devices are recommended in therapeutic settings because of their ability to treat larger areas.

When internal treatment is necessary for severe medical conditions, intravenous devices are used under the guidance of a qualified professional.

Adelyn Cline Beauty Machine Manufacturer is PDT Photon Therapy Device manufacturer, provide all types of PDT Photon Therapy Devices. If you look for PDT Photon Therapy Devices or Hydrafacial Machine, contact us via below form or directly send email to

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